Comparación de dos técnicas de implantación de lentes intracorneales en ojos de conejo

  1. I Martínez-Soroa
  2. J Mendicute-del-Barrio
  3. AB Asensio-Huerga
  4. I Madarieta-Pardo
  5. JI Alava-Marquínez
  6. N Garagorri-Gantxegi
  7. P Aldazábal-Amas
Revista:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Ano de publicación: 2005

Volume: 80

Número: 10

Páxinas: 581-587

Tipo: Artigo

DOI: 10.4321/S0365-66912005001000005 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Archivos de la Sociedad Española de Oftalmologia

Obxectivos de Desenvolvemento Sustentable

Resumo

Objective: To compare two different surgical techniques of intracorneal lens implantation. To determine the incidence of corneal and lens complications in two groups of rabbits subjected to such surgery. Method: The first group (7 rabbits) initially had a keratectomy performed with the microkeratome following which the corneal flap was sutured to the stromal layer. In the second group (7 rabbits), a pocket-shaped stromal dissection was performed manually. Both groups of rabbits had a secondary lens implantation in the corneal inlay. The follow up period was of 2 months duration. Results: The incidence of corneal edema in the first month was higher in group 1 (71.4%) than in group 2 (14.3%) (p= 0.0155); during the second month, the incidence was 42.9% in group 1 and 28.6% in group 2 (p= 0.2927). Flap dislocation and retraction of the flap was seen in 4 of the 7 rabbits in group 1, whereas no complication of this type was observed in the manual pocket group (group 2). The incidence of lens subluxation was 28.6% in group 1 and 0% in group 2. Finally, there was a 71.4% (5/7) loss of the intracorneal lens in the rabbits treated with the microkeratome (group 1) while only 1 of 7 rabbits (14.3%) lost the lens in group 2 (P= 0.0155). Discussion: Eyes in which the corneal pocket shape was made by manual stromal dissection had a higher stability of the lens and less post-operative corneal complications.

Referencias bibliográficas

  • Barraquer, JI. (1966). Modification of refraction by means of intracorneal inclusions. Int Ophthalmol Clin. 6. 53-78
  • Deg, JK, Binder, PS. (1988). Histopathology and clinical bahavior of polysulfone intracorneal implants in the baboon model: Polysulfone lens implants. Ophthalmology. 95. 506-515
  • Horgan, SE, Fraser, SG, Choyce, DP, Alexander, WL. (1996). Twelve year follow-up of unfenestrated polysulfone intracorneal lenses in human sighted eyes. J Cataract Refract Surg. 22. 1045-1051
  • McDonald, MB, McCarey, BE, Storie, B, Beuerman, RW, Salmeron, B, van Rij, G. (1993). Assessment of long-term corneal response to hydrogel intrastromal lenses implanted in monkey eyes for up to five years. J Cataract Refract Surg. 19. 213-222
  • Crawford, GJ, Chirila, TV, Vijayasekaran, S, Dalton, PD, Constable, IJ. (1996). Preliminary evaluation of a hydrogel core-and-skirt keratoprosthesis in the rabbit cornea. J Refract Surg. 12. 525-529
  • Barraquer, JI, Gomez, ML. (1997). Permalens hydrogel intracorneal lenses for spherical ametropia. J Refract Surg. 13. 342-348
  • Garagorri Gantxegi, N. (2000). Desarrollo de un nuevo polímero con actividad antielastasa. Universidad del País Vasco.
  • Beekhuis, WH, McCarey, BE. (1985). Hydration stability of intracorneal hydrogel implants. Invest Ophthalmol Vis Sci. 26. 1634-1636
  • Beekhuis, WH, McCarey, BE, Waring, GO, van Rij, G. (1986). Hydrogel keratophakia: a microkeratome dissection in the monkey model. Br J Ophthalmol. 70. 192-198
  • McCarey, BE, van Rij, G, Beekhuis, WH, Waring, GO 3rd. (1986). Hydrogel keratophakia: a freehand pocket dissection in the monkey model. Br J Ophthalmol. 70. 187-191
  • McCarey, BE. (1990). Current status of refractive surgery with synthetic intracorneal lenses: Barraquer lecture. Refract Corneal Surg. 6. 40-46
  • Krachmer, JH, Mannis, MJ, Holland, EJ. (1997). Fundamentals of cornea and external disease. Mosby. Sant Louis.
  • Beekhuis, WH, McCarey, BE, van Rij, G, Waring, GO 3rd. (1987). Complications of hydrogel intracorneal lenses in monkeys. Arch Ophthalmol. 105. 116-122
  • McCarey, BE, Schmidt, FH. (1990). Modeling glucose distribution in the cornea. Curr Eye Res. 9. 1025-1039
  • McCarey, BE, Andrews, DM. (1981). Refractive keratoplasty with intrastromal hydrogel lenticular implants. Invest Ophthalmol Vis Sci. 21. 107-115
Fonte de datos: Dialnet